Bsa protein

DiVA - Sökresultat - DiVA Portal

Here, we describe the molecular interactions of AA with two serum proteins, human serum albumin (HSA) and bovine serum albumin (BSA Anisomelic acid, one of the major compounds in Anisomeles malabarica (L.) R. Br., is a cembrane-type diterpenoid, which can be synthesized chemically . Anisomelic acid has also been previously isolated from A. malabarica and A. indica and it has been shown to be cytotoxic to KB cells [5, 6]. Anisomelic acid (AA) (Fig. S1†) is a diterpenoid compound isolated from the medicinal plant Anisomeles malabarica, 7 which we have previously shown to be cytotoxic to oral and cervical cancer cells. 8 Recently, we have shown that AA induces apoptosis and cause cell cycle arrest in SiHa cervical cancer cells by specifically down-regulating the Anisomelic acid (AA), one of the major compounds in Anisomeles malabarica, was tested for its cytotoxicity and apoptosis-inducing potential in breast and cervical cancer cells. The MTT assay for Anisomelic acid, is one of the major compounds in Anisomeles malabarica (L.) R. Br., is a cembrane type diterpenoid, which can be synthesized chemically.

Biochemical Pharmacology. 89:171–184. petroleum ether extract of plant contains a triterpenic acid known as betulinic acid [3] while the hexane extract consists of β-sitosterol and diterpenoids (ovatodiolide and anisomelic acid) [4]. The aerial parts contain anisomelolide, malabaric acid, 2-acetoxymalabaric acid, anisomelyl acetate, anisomelol and … Pharmacy AA abbreviation meaning defined here. What does AA stand for in Pharmacy? Get the top AA abbreviation related to Pharmacy. Anisomelic acid | C20H26O4 | CID 5358705 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.

CAM, cIAP2, HPV: 5 : 2013: Analysis of the Cytotoxic Potential of Anisomelic Acid Isolated from Anisomeles malabarica. A pharmaceutical composition for anti-viral cancer treatment in mammals, comprising a therapeutically effective amount of Anisomelic acid or salts thereof. The pharmaceutical composition may comprise Anisomelic acid or salt thereof in an oil-in-water emulsion, for example in an isotropic mixture of at least one oil and at least one surfactant or, alternatively, in a hydrophilic solvent and a Anisomelic acid, is one of the major compounds in Anisomeles malabarica (L.) R. Br., is a cembrane type diterpenoid, which can be synthesized chemically.

Synthesis and Evaluation of Anisomelic acid-like Compounds

In a pioneering study, we showed that a naturally occurring compound (anisomelic acid), as well as synthetic derivatives that we have developed based on this compound, effectively degrade the HPV E6 and E7 oncoproteins, i.e., the carcinogenic proteins in the virus that are known to play a key role in promoting the devel opment of HVP-positive cancers, says cell biology professor John Eriksson Paul P, Kumar Rajendran S*, Peuhu E*, Alshatwi AA, Mohammad AA, Hietanen S, and Eriksson JE (2014): Novel action modality of the diterpenoid anisomelic acid causes depletion of E6 and E7 viral oncoproteins in HPV-transformed cervical carcinoma cells. Biochemical Pharmacology. 89:171–184.

DiVA - Sökresultat - DiVA Portal

Anisomeles malabarica (Lamiaceae) is an aromatic, densely pubescent, perennial herb, 1.2-2 m in height. The leaves of Anisomeles malabarica are used against colic, convulsion and tetanus. 2. Our recent studies have demonstrated that a plant-derived diterpenoid compound, anisomelic acid (AA), induces apoptosis in cervical cancer cells. In this work, we describe the development of a folic acid (FA)-targeted AA delivery system using chitosan-coated rod-shaped mesoporous silica particles (Chitosan-NR-MSP). ANISOMELIC-ACID Plant -- -- Wealth of India.

Some people take it This is the definition of a strong acid as the term is used in chemistry.
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Scientific Reports (IF 3.998) Pub Cloxyquin preferentially binds into the fatty acid binding site 5 (FA5) of the BSA binding of anisomelic acid: Spectroscopy and molecular dynamic simulations. Twenty-carbon compounds derived from MEVALONIC ACID or deoxyxylulose phosphate. Top Interacting Genes.

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Synthesis and Evaluation of Anisomelic acid-like Compounds

13:2002-2006. Activities (22) Anthelmintic AntiHIV EC50=2.0 ug/ml Kashiwada, Y terpenoid compounds, including Anisomelic Acid (Arisawa et al. 1986), and 15 essential oil constituents (Yadava & Barsainya 1998). Anisomeles malabarica has been shown to possess Anisomelic Acid, as well as Anisomelolide, Malabaric Acid, 2-Acetoxymalabaric Acid, Anisomelyl Acetate and Anisomelol (Preethy et al. 2013), and essential oils. Anisomelic acid (AA) is a macrocyclic cembranolide compound extracted from Anisomeles herbal species. Recently, we have shown that AA possesses both anti-cancer and anti-viral activity.